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San Francisco (/ˌsæn frənˈsɪskoʊ/; Spanish for "Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California in the United States. The city proper is the fourth most populous in California and 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of 46.9 square miles (121 square kilometers), at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include SF, San Fran, The City, Frisco, and Baghdad by the Bay.

San Francisco and the surrounding San Francisco Bay Area are a global center of economic activity and the arts and sciences, spurred by leading universities, high-tech, healthcare, FIRE, and professional services sectors. As of 2020, the metropolitan area, with 6.7 million residents, ranked 5th by GDP ($874 billion) and 2nd by GDP per capita ($131,082) across the OECD countries, ahead of global cities like Paris, London, and Singapore. San Francisco anchors the 13th most populous metropolitan statistical area in the United States with 4.6 million residents, and the fourth-largest by aggregate income and economic output, with a GDP of $669 billion in 2021. The wider San Jose–San Francisco–Oakland, CA Combined Statistical Area is the fifth most populous, with 9.5 million residents, and the third-largest by economic output, with a GDP of $1.25 trillion in 2021. In the same year, San Francisco proper had a GDP of $236.4 billion, and a GDP per capita of $289,990. San Francisco was ranked seventh in the world and third in the United States on the Global Financial Centres Index as of March 2022.

Guizhou, referred to as "Guizhou" or "Gui" for short, is a provincial administrative region of the people's Republic of China. Guiyang, the provincial capital, is located in the hinterland of southwest China. It is a transportation hub in southwest China and an important part of the Yangtze River economic belt. China's first national big data comprehensive experimental area, world-famous mountain tourism destinations and major mountain tourism provinces, national ecological civilization experimental area, inland open economic experimental area. It is bounded by 24 °37 degrees north latitude 29 °13 'longitude, 103 °36 degrees east longitude, 109 °35 degrees east longitude, Sichuan and Chongqing to the north, Hunan to the east, Guangxi to the south, and Yunnan to the west. The topography of Guizhou is high in the west and low in the east, tilting from the middle to the north, east and south. The geomorphology of the province can be summarized as follows: the topography is high in the west and low in the east, tilted from the middle to the north, east and south, and the landform is plateau and mountainous area.
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