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San Francisco (/ˌsæn frənˈsɪskoʊ/; Spanish for "Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California in the United States. The city proper is the fourth most populous in California and 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of 46.9 square miles (121 square kilometers), at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include SF, San Fran, The City, Frisco, and Baghdad by the Bay.

San Francisco and the surrounding San Francisco Bay Area are a global center of economic activity and the arts and sciences, spurred by leading universities, high-tech, healthcare, FIRE, and professional services sectors. As of 2020, the metropolitan area, with 6.7 million residents, ranked 5th by GDP ($874 billion) and 2nd by GDP per capita ($131,082) across the OECD countries, ahead of global cities like Paris, London, and Singapore. San Francisco anchors the 13th most populous metropolitan statistical area in the United States with 4.6 million residents, and the fourth-largest by aggregate income and economic output, with a GDP of $669 billion in 2021. The wider San Jose–San Francisco–Oakland, CA Combined Statistical Area is the fifth most populous, with 9.5 million residents, and the third-largest by economic output, with a GDP of $1.25 trillion in 2021. In the same year, San Francisco proper had a GDP of $236.4 billion, and a GDP per capita of $289,990. San Francisco was ranked seventh in the world and third in the United States on the Global Financial Centres Index as of March 2022.

Gaozhou, county-level cities under the jurisdiction of Guangdong Province, important small and medium-sized cities of Beibu Gulf Urban agglomeration in China, economically strong counties (cities) in mountainous areas of Guangdong Province, educational counties (cities) of Guangdong Province, and county medical centers of Guangdong Province, the comprehensive strength of economic and social development has long been in the forefront of Guangdong counties. Gaozhou is located in the southwest of Guangdong Province, southwest of Guangdong, near the South China Sea in the east, Jianjiang Plain in the south, Guangxi in the west, Yunkai Mountain in the north, six counties and cities in Guangdong and Guangxi in the west, Yangchun City and Dianbai District in the east, Maonan District in the south and Xinyi City in the north, bordering Huazhou City in the southwest and Beiliu City in Guangxi in the northwest. Gaozhou, formerly known as Maoming County and Gaozhou County, evolved from the administration of Maoming County by Gaozhou Prefecture (Road) in the Yuan Dynasty, while the place name of "Gaozhou" evolved from "Gaoliang". Before the Sui Dynasty, Gaoliang County was in the area of Enping and Yangjiang; since the Sui and Tang dynasties
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