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Baltimore (/ˈbɔːltɪmɔːr/ BAWL-tim-or, locally: /bɔːldəˈmɔːr/ bawl-da-MOR or /ˈbɔːlmər/ BAWL-mər) is the most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic, and the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an independent city by the Constitution of Maryland[a] in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the 20th largest metropolitan area in the country. Baltimore is located about 40 miles (64 km) north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area (CSA), the third-largest CSA in the nation, with a 2021 estimated population of 9,946,526.

Prior to European colonization, the Baltimore region was used as hunting grounds by the Susquehannock Native Americans, who were primarily settled further northwest than where the city was later built. Colonists from the Province of Maryland established the Port of Baltimore in 1706 to support the tobacco trade with Europe, and established the Town of Baltimore in 1729. The first printing press and newspapers were introduced to Baltimore by Nicholas Hasselbach and William Goddard respectively, in the mid-18th century.

The Battle of Baltimore was a pivotal engagement during the War of 1812, culminating in the failed British bombardment of Fort McHenry, during which Francis Scott Key wrote a poem that would become "The Star-Spangled Banner", which was eventually designated as the American national anthem in 1931. During the Pratt Street Riot of 1861, the city was the site of some of the earliest violence associated with the American Civil War.

Tumushuke, a county-level city directly under the jurisdiction of Xinjiang Uygur Autonomous region, implements a division-city management system with the third Division of the Xinjiang production and Construction Corps, which is managed by the Xinjiang production and Construction Corps. Established with the approval of the State Council in 2002, it now covers an area of 2003 square kilometers and has a total resident population of 255600 in 2018. Located in the center of Kashgar, Aksu, Kezhou and Hotan, bordering the five countries of Central Asia, there are five first-class opening ports available to the outside world, which is the forefront of China's opening to the countries of Central Asia, West Asia and South Asia. It is also an important city along the New Eurasian Continental Bridge of the China-Kyrgyzstan-Ukraine Railway, which is being built to the west of Kashgar. Tumushuke has a pleasant climate and is a production base for cotton, grain and fruit. The southwest of the city has a storage capacity of 700 million cubic meters
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